Tris(3-hydroxypropyltriazolylmethyl)amine
CAS No. : 760952-88-3
(Synonyms: THPTA)
| Size | Price | Stock |
|---|---|---|
| 50mg | $10 | In-stock |
| 100mg | $11 | In-stock |
| 250mg | $20 | In-stock |
| 1g | $76 | In-stock |
| 2g | $151 | In-stock |
| 5g | $361 | In-stock |
| 25g | $1216 | In-stock |
| 50 g | Get quote | |
| 100 g | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-W021042 |
| M.Wt: | 434.50 |
| Formula: | C18H30N10O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic);H2O : ≥ 175 mg/mL |
Tris(3-hydroxypropyltriazolylmethyl)amine (THPTA) is an accelerating ligand in the copper-catalyzed azide-alkyne cycloaddition reaction (CuAAC) and protects cells from oxidants generated by copper-catalyzed reduction of oxygen by ascorbate. In addition, Tris(3-hydroxypropyltriazolylmethyl)amine can also protect the histidine moiety of biomolecules in a manner proportional to the ligand concentration[1][2][3][4][5].
In Vitro:Tris(3-hydroxypropyltriazolylmethyl)amine (1.25 mM, 1 h) intercepts and quickly reduce reactive oxygen species generated by the ascorbate-driven reduction of dissolved O2 without compromising the CuAAC reaction rate very much[1].
Tris(3-hydroxypropyltriazolylmethyl)amine (250 μM, 1-5 min) reverses the toxic effect of Cu-ascorbate effect in a dose-dependent manner at a 5:1 ligand:Cu ratio, preserving the viability of HeLa, Chinese hamster ovary (CHO), and Jurkat cells[2].
Tris(3-hydroxypropyltriazolylmethyl)amine (125 μM, 5 min) accelerates the click reaction and allows the cells to survive at a copper concentration of 50 μM in HeLa cells[4].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Tris(3-hydroxypropyltriazolylmethyl)amine
- Cat. No.:
- HY-W021042
- Quantity:
Your information is safe with us.