Enalapril (maleate)


CAS No. : 76095-16-4

(Synonyms: MK-421 (maleate))

76095-16-4
Price and Availability of CAS No. : 76095-16-4
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5g $170 In-stock
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Cat. No. : HY-B0331A
M.Wt: 492.52
Formula: C24H32N2O9
Purity: >98 %
Solubility: DMSO : ≥ 50 mg/mL;H2O : 33.33 mg/mL (ultrasonic;warming)
Introduction of 76095-16-4 :

Enalapril (MK-421) maleate, the active metabolite of enalapril, is an angiotensin-converting enzyme (ACE) inhibitor. IC50 & Target:ACE[1]. In Vivo:Enalapril (MK-421) is a prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to enalaprilat following oral administration. Enalapril (MK-421) is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Enalapril may be used to treat essential or renovascular hypertension and symptomatic congestive heart failure[1].

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