3-Methyl-2-oxobutanoic acid


CAS No. : 759-05-7

759-05-7
Price and Availability of CAS No. : 759-05-7
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Cat. No. : HY-W006057
M.Wt: 116.12
Formula: C5H8O3
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 759-05-7 :

3-Methyl-2-oxobutanoic acid is a precursor of pantothenic acid in Escherichia coli. In Vitro: 3-Methyl-2-oxobutanoic acid (alpha-Ketoisovaleric acid) is a precursor of pantothenic acid in Escherichia coli[1]. 3-Methyl-2-oxobutanoic acid (alpha-Ketoisovaleric acid) enhances alpha-ketoisocaproic acid and alpha-keto-beta-methyl-n-valeric acid, but diminishes the corresponding amino acids, and causes an early decline of ornithine along with a late augmentation of plasma arginine[2]. In Vivo: 3-Methyl-2-oxobutanoic acid (alpha-Ketoisovaleric acid) induces convulsions through GABAergic and glutamatergic mechanisms in rats[3].

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