Cefmenoxime (hydrochloride)
CAS No. : 75738-58-8
(Synonyms: SCE-1365 (hydrochloride))
| Size | Price | Stock |
|---|---|---|
| 100mg | $80 | In-stock |
| 500mg | $200 | In-stock |
| 1g | $300 | In-stock |
| 5g | $600 | In-stock |
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| Cat. No. : | HY-B0875 |
| M.Wt: | 529.79 |
| Formula: | C16H17N9O5S3.1/2 HCl |
| Purity: | >98 % |
| Solubility: | DMSO : 65 mg/mL (ultrasonic;warming);H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) |
Cefmenoxime (SCE-1365) hydrochloride is a new semisynthetic cephalosporin antibiotic. Cefmenoxime has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria[1][2].
In Vitro: Cefmenoxime (SCE-1365) hydrochloride inhibits at least 90% of strains tested (MIC90) ranged from 0.06 to 8 μg/mL for the Enterobacteriaceae[1].
Cefmenoxime (SCE-1365) hydrochloride inhibits MIC90 values for gram-positive cocci are 0.015 and ≤0.008 μg/mL for Streptococcus pneumoniae and Streptococcus pyogenes, respectively, and 2 μg/mL for S. aureus[1].
Cefmenoxime (SCE-1365) hydrochloride against Haemophilus influenzae, Neisseria gonorrhoeae, and Neisseria meningitidis with MIC90 values ranging from ≤0.008 to 0.25 μg/mL[1].
In Vivo: Cefmenoxime (SCE-1365) hydrochloride (40 mg/kg; i.h.; daily, for 7 d; male Jcl:ICR mice) improves the survival rate of mice infected with lung bacteria[2].
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