Fmoc-NH-PEG8-CH2CH2COOH


CAS No. : 756526-02-0

756526-02-0
Price and Availability of CAS No. : 756526-02-0
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100mg $20 In-stock
250mg $25 In-stock
1g $62 In-stock
5g $304 In-stock
10g $546 In-stock
25g $1221 In-stock
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Cat. No. : HY-W040135
M.Wt: 663.75
Formula: C34H49NO12
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 756526-02-0 :

Fmoc-NH-PEG8-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

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