NH2-PEG2-C2-Boc
CAS No. : 756525-95-8
| Size | Price | Stock |
|---|---|---|
| 250mg | $6 | In-stock |
| 1g | $15 | In-stock |
| 5g | $56 | In-stock |
| 10g | $104 | In-stock |
| 25g | $159 | In-stock |
| 100g | $634 | In-stock |
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| 500 g | Get quote | |
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| Cat. No. : | HY-42149 |
| M.Wt: | 233.30 |
| Formula: | C11H23NO4 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
NH2-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. NH2-PEG2-C2-Boc is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2].
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- NH2-PEG2-C2-Boc
- Cat. No.:
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