Boc-NH-PEG4-CH2CH2COOH


CAS No. : 756525-91-4

756525-91-4
Price and Availability of CAS No. : 756525-91-4
Size Price Stock
100mg $9 In-stock
250mg $12 In-stock
1g $32 In-stock
5g $158 In-stock
10g $288 In-stock
25g $489 In-stock
100g $1225 In-stock
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Cat. No. : HY-W040132
M.Wt: 365.42
Formula: C16H31NO8
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 756525-91-4 :

Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1]. Boc-NH-PEG4-CH2CH2COOH is also a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC)[2]. In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

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