Fomepizole
CAS No. : 7554-65-6
(Synonyms: 4-Methylpyrazole)
| Size | Price | Stock |
|---|---|---|
| 5g | $10 | In-stock |
| 10g | $13 | In-stock |
| 25g | $19 | In-stock |
| 100g | $62 | In-stock |
| 500g | $269 | In-stock |
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| 2 kg | Get quote | |
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| Cat. No. : | HY-B0876 |
| M.Wt: | 82.11 |
| Formula: | C4H6N2 |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (ultrasonic);DMSO : ≥ 100 mg/mL |
Fomepizole (4-Methylpyrazole) is a potent cytochrome P450 (CYP2E1) inhibitor. Fomepizole is a competitive inhibitor of the enzyme alcohol dehydrogenase. Fomepizole blocks further conversion of methanol and ethylene glycol to toxic metabolites. Fomepizole has the potential for an antidote for ethylene glycol or methanol poisoning[1][2][3]. In Vivo: Pretreatment with Fomepizole (4-Methylpyrazole; 25 mg/kg; IP) prolongs ethanol neurobehavioral toxicity in CD-1 mice[4]
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