L-Leucinol


CAS No. : 7533-40-6

(Synonyms: (+)-Leucinol)

7533-40-6
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Cat. No. : HY-W015876
M.Wt: 117.19
Formula: C6H15NO
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 7533-40-6 :

L-Leucinol ((+)-Leucinol) is a competitive aminopeptidase inhibitor with a Ki value of 17 μM. As a dietary intake inhibitor, L-Leucinol reduces the basal dietary leucine intake in rats via microinjection into the rat anterior piriform cortex[1][2]. In Vitro:L-leucinol interacts with the two metal ions in the binuclear active site of Co (II)-substituted aminopeptidase from Aeromonas proteolytica, altering the electronic symmetry or coordination geometry of Co2+ ions, which is evidenced by the red shift of absorption peaks and changes in molar absorptivity[1].

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