HEPES (sodium)


CAS No. : 75277-39-3

75277-39-3
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Cat. No. : HY-108535
M.Wt: 260.29
Formula: C8H17N2NaO4S
Purity: >98 %
Solubility: DMSO : 25 mg/mL (ultrasonic)
Introduction of 75277-39-3 :

HEPES sodium, a nonvolatile zwitterionic chemical buffering agent, is broadly applied in cell culture. HEPES sodium is effective at pH 6.8 to 8.2. HEPES sodium is also a potent inducer of lysosome biogenesis[1][2][3]. In Vitro: HEPES maintains superhydrophilicity of titanium for at least 3 months and resulted in a continuous retention of bioactivity and osteoconductivity[1].
HEPES drives lysosome biogenesis, affects MiT/TFE cytoplasmic-nuclear distribution, disrupts global cellular transcriptional profiles, resulting the activation of a MiT/TFE-dependent lysosomal-autophagic gene network in cultured RAW264.7 cells[3].

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