Lovastatin hydroxy acid (sodium)
CAS No. : 75225-50-2
(Synonyms: Mevinolinic acid (sodium))
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|---|---|---|
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| 10mg | $380 | In-stock |
| 25mg | $760 | In-stock |
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| Cat. No. : | HY-123672 |
| M.Wt: | 444.54 |
| Formula: | C24H37NaO6 |
| Purity: | >98 % |
| Solubility: | DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C) |
Lovastatin hydroxy acid sodium (Mevinolinic acid sodium) is a highly potent inhibitor of HMG-CoA reductase with a Ki of 0.6 nM[1]. IC50 & Target:Ki: 0.6 nM (HMG-CoA reductase)[1] In Vitro: Mevinolin in the hydroxy-acid form, mevinolinic acid, is a potent competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase [mevalonate: NADP+ oxidoreductase (CoA-acylating)][1].
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