Taprenepag
CAS No. : 752187-80-7
(Synonyms: CP-544326)
| Size | Price | Stock |
|---|---|---|
| 5mg | $75 | In-stock |
| 10mg | $120 | In-stock |
| 25mg | $250 | In-stock |
| 50mg | $400 | In-stock |
| 100mg | $650 | In-stock |
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| Cat. No. : | HY-14899 |
| M.Wt: | 478.52 |
| Formula: | C24H22N4O5S |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
Taprenepag (CP-544326) is a potent and selective prostaglandin EP(2) agonist with IC50s of 10 and 15 nM for human and rat EP2, respectively. Taprenepag shows selectivity for EP2 over other EP receptors (IC50s>3200 nM for EP1, EP3, and EP4) and a panel of 37 G protein-coupled receptors[1]. In Vitro: Taprenepag (CP-544326) (0.01-1000 nM) increases cAMP levels in HEK293 cells expressing human EP2 (EC50=2.8 nM). Taprenepag has poor corneal permeability in an ex vivo rabbit corneal model[1].
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