Acridine Orange 10-Nonyl Bromide
CAS No. : 75168-11-5
(Synonyms: Nonylacridine orange)
| Size | Price | Stock |
|---|---|---|
| 5mg | $39 | In-stock |
| 10mg | $66 | In-stock |
| 25mg | $140 | In-stock |
| 50mg | $222 | In-stock |
| 100mg | $344 | In-stock |
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| Cat. No. : | HY-D0993 |
| M.Wt: | 472.50 |
| Formula: | C26H38BrN3 |
| Purity: | >98 % |
| Solubility: | DMSO : 20 mg/mL (ultrasonic;warming;heat to 60°C) |
Acridine Orange 10-Nonyl Bromide is a fluorescent probe for cardiolipin (λex: 489 nm, λem: 525 nm).
In Vitro:Acridine Orange 10-Nonyl Bromide is a fluorescent probe for cardiolipin (λex: 489 nm, λem: 525 nm) which can be used to quantify the cardiolipin in isolated mitochondria. In 15 min at 20°C, Acridine Orange 10-Nonyl Bromide at 4.75 μM saturates the mitochondrial binding sites present in 1.5 X 106 cells[1].
When Acridine Orange 10-Nonyl Bromide interacts with cardiolipin, the dye excitation and emission wave lengths shift from 496 and 525 nm to 450 and 640 nm, respectively. Increasing amounts of cardiolipin (0 to 30 μM) and other acidic phospholipids in thin-walled vesicles added to Acridine Orange 10-Nonyl Bromide (45 μM) changes the red fluorescence emission measured at 640 nm according to the liposome composition[2].
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