CID 5951923


CAS No. : 749872-43-3

749872-43-3
Price and Availability of CAS No. : 749872-43-3
Size Price Stock
5mg $110 In-stock
10mg $140 In-stock
25mg $290 In-stock
50mg $470 In-stock
100mg $750 In-stock
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Cat. No. : HY-W011044
M.Wt: 382.39
Formula: C16H18N2O7S
Purity: >98 %
Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 749872-43-3 :

CID 5951923 is a potent inhibitor of Krüppel-like factor 5 (KLF5), with an IC50 of 603 nM. CID 5951923 can inhibit proliferation of cancer cells in vitro[1]. IC50 & Target: IC50: 603 nM (KLF5)[1] In Vitro: CID 5951923 (1 nM-100 μM; 48 h) inhibits proliferation of DLD-1 cells in a dose-dependent manner[1].
CID 5951923 (10 μM; 24 h) significantly decreases endogenous KLF5 levels in the DLD-1 cells, increases phosphorylation levels of pEGFFpY1068, and downregulated EGR1[1].
CID 5951923 (10 μM) inhibits proliferation of cancer cell lines mainly in highly express KLF5 cells[1].

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