Magnesium sulfate, for cell culture
CAS No. : 7487-88-9
| Size | Price | Stock |
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| Cat. No. : | HY-Y1267D |
| M.Wt: | 120.37 |
| Formula: | MgSO4 |
| Purity: | >98 % |
| Solubility: | H2O : ≥ 100 mg/mL |
Magnesium sulfate, for cell culture is a bioreagent. Magnesium sulfate is a calcium antagonist and a potent L-type calcium channel inhibitor, as well as a tocolytic. Magnesium sulfate has anti-inflammatory, anticonvulsant, vasodilatory, and neuroprotective effects. Magnesium sulfate can be used in the research of diseases such as preeclampsia/eclampsia[1][2][3][4][5][6].
In Vitro:Magnesium sulfate (3 mM) for cell culture inhibits phosphatidylinositol-4,5-bisphosphate-specific phospholipase C activity and subsequent calcium release in cultured myometrial cells[2].
Magnesium sulfate (20 mM; 6 h) for cell culture inhibits the LPS (HY-D1056)-induced inflammatory molecules production and NF-κB activation in RAW264.7 cells[3].
In Vivo:Magnesium sulfate (intraperitoneal injection; 270 mg/kg, followed by 27 mg/kg every 20 minutes for 4 hours, and then an additional 270 mg/kg) for cell culture reduces LPS (HY-D1056)-induced inflammation-associated brain injury in fetal mice[4].
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