Cefpiramide (sodium)
CAS No. : 74849-93-7
(Synonyms: SM-1652; Wy-44635)
| Size | Price | Stock |
|---|---|---|
| 5mg | $90 | In-stock |
| 10mg | $144 | In-stock |
| 25mg | $290 | In-stock |
| 50mg | $435 | In-stock |
| 100mg | $652 | In-stock |
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| Cat. No. : | HY-B0798 |
| M.Wt: | 634.62 |
| Formula: | C25H23N8NaO7S2 |
| Purity: | >98 % |
| Solubility: | DMSO : 58.33 mg/mL (ultrasonic) |
Cefpiramide sodium (SM-1652) is a semisynthetic cephalosporin with broad-spectrum antibacterial activity. Cefpiramide sodium shows strong antibacterial effect on both gram-positive bacteria and gram-negative bacteria. Cefpiramide sodium is moderately susceptible to β-lactamase[1][2].
IC50 & Target:Bacterial[1][2]
In Vitro:Cefpiramide (0-2048 μg/mL; 16-18 hours) sodium (SM-1652) shows good activity to against most non-fermentative Gram-negative bacilli and Enterococci (32 μg/mL with 97% inhibition)[1].
Cefpiramide (0-2048 μg/mL; 16-18 hours) sodium exhibits high effective to against Pseudomonas aeruginosa with MIC[50] and MIC[90] values of 4 μg/mL and 16 μg/mL separately[1].
In Vivo:Cefpiramide (25 mg/kg; i.v.; once) sodium (SM-1652) shows anti-Streptococcus pneumoniae activity in experimental pneumococcal meningitis[2].
Cefpiramide (25 mg/kg; i.v.; once) sodium reduces bacteria in CSF more than 10[4] CFU/ml[2].
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