Pyronaridine
CAS No. : 74847-35-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $99 | Get quote |
| 10mg | $142 | Get quote |
| 25mg | $255 | Get quote |
| 50mg | $364 | Get quote |
| 100mg | $525 | Get quote |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-14749 |
| M.Wt: | 518.05 |
| Formula: | C29H32ClN5O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Pyronaridine is an orally active Mannich base anti-malarial agent. Pyronaridine is active against P. falciparum and Echinococcus granulosus infection[1][2].
In Vitro: Pyronaridine (24 h) shows anti-P. falciparum activity with an IC50 value of 1.53-3.94 nM[1].
In Vivo: Pyronaridine (57 mg/kg, oral administration, q.d. for 30 days) reduces the parasitic burden in the Echinococcus granulosus-infected mice[2].
Pyronaridine (57 mg/kg, intraperitoneal injection, q.d. for 3 days) reduces the parasitic burden in secondarily infected (cysts) mice[2].
Pyronaridine (57 mg/kg, intraperitoneal injection, for a single dose) exhibits a higher exposure in the liver than in the plasma in male ICR mice[2].
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