Methylophiopogonanone B
CAS No. : 74805-91-7
| Size | Price | Stock |
|---|---|---|
| 1mg | $100 | In-stock |
| 5mg | $250 | In-stock |
| 10mg | $400 | In-stock |
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| Cat. No. : | HY-N2438 |
| M.Wt: | 328.36 |
| Formula: | C19H20O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Methylophiopogonanone B is a homoisoflavonoid compound. Methylophiopogonanone B can be isolated from O. japonicus root. Methylophiopogonanone B promotes Rho activation and tubulin depolymerization. Methylophiopogonanone B significantly increases GTP-Rho, but not GTP-Rac or GTP-CDC42. Methylophiopogonanone B induces cell morphological change via melanocyte dendrite retraction and stress fiber formation. Methylophiopogonanone B exhibits strong antioxidant activity. Methylophiopogonanone B can be used in the research of cervical cancer[1][2].
In Vitro:Methylophiopogonanone B exhibits strong antioxidant activity[1].
Methylophiopogonanone B (1 μM; 6 h) induces dendrite retraction and actin cytoskeleton rearrangement in normal epidermal melanocytes[2].
Methylophiopogonanone B (1-10 μM; 6 h) induces dose-dependent stress fiber formation and microtubule disorganization in HeLa cells[2].
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