C12-Ceramide


CAS No. : 74713-60-3

(Synonyms: N-Lauroyl-D-erythro-sphingosine; N-Laurylsphingosine)

74713-60-3
Price and Availability of CAS No. : 74713-60-3
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5mg $180 In-stock
10mg $290 In-stock
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Cat. No. : HY-100353
M.Wt: 481.79
Formula: C30H59NO3
Purity: >98 %
Solubility: DMSO : 2.5 mg/mL (ultrasonic)
Introduction of 74713-60-3 :

C12-Ceramide (N-Lauroyl-D-erythro-sphingosine), a naturally occurring ceramide, is formed by hydrolysis of C12 sphingomyelin. C12-Ceramide can enhance the Doxorubicin toxicity in MDA-MB-231 cells. C12-Ceramide also can be used to diagnose types A and B Niemann-Pick disease[1][1]. In Vitro: C12-Ceramide (1 μM; 24-72 h) enhances the liposomal Doxorubicin toxicity in MDA-MB-231 cells[1].

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