Hydroxychloroquine (sulfate)


CAS No. : 747-36-4

(Synonyms: HCQ (sulfate))

747-36-4
Price and Availability of CAS No. : 747-36-4
Size Price Stock
50mg $60 In-stock
100mg $90 In-stock
200mg $135 In-stock
500mg $216 In-stock
1g $286 In-stock
5g $514 In-stock
10g $668 In-stock
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Cat. No. : HY-B1370
M.Wt: 433.95
Formula: C18H28ClN3O5S
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic);H2O : 110 mg/mL (ultrasonic;warming)
Introduction of 747-36-4 :

Hydroxychloroquine sulfate (HCQ sulfate) is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine sulfate is efficiently inhibits SARS-CoV-2 infection in vitro[1][2][3]. IC50 & Target:Antimalarial[1], TLR7/9[2] In Vitro: Hydroxychloroquine sulfate is a synthetic antimalarial drug derived from 4-aminoquinoline; it has been used for several decades for the treatment of some rheumatic diseases such as rheumatoid arthritis (RA)[1]. Five micromolar Hydroxychloroquine sulfate or chloroquine also has no measurable effect on intracellular pH, although these concentrations can inhibit TLR9 or 7 signaling induced by DNA or RNA ligands[2]. In Vivo: Hydroxychloroquine sulfate is prescribed for the treatment of lupus, and both Hydroxychloroquine sulfate and its analog chloroquine inhibit TLR7 and 9 signaling[2].

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