BIO-013077-01
CAS No. : 746667-48-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $190 | In-stock |
| 10mg | $290 | In-stock |
| 25mg | $490 | In-stock |
| 50mg | $710 | In-stock |
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| Cat. No. : | HY-118810 |
| M.Wt: | 287.32 |
| Formula: | C17H13N5 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
BIO-013077-01 is a pyrazole TGF-β inhibitor[1]. In Vitro: A wide range of cellular functions such as cell proliferation, differentiation, adhesion, migration, and apoptosis are regulated by TGF-β superfamily members. The TGF-βs include the three major TGF-β isoforms, TGF-β1, TGF-β2, and TGF-β3 which are expressed in mammals. TGF-β transduces signals through a complex of two related but structurally and functionally distinct serine/threonine kinase receptors, termed type 1 and type II. Deregulation of TGF-β signaling has been also implicated in various human diseases including cancer, pancreatic diseases, and hematological malignancies[1].
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