m-PEG3-Amine
CAS No. : 74654-07-2
| Size | Price | Stock |
|---|---|---|
| 250mg | $15 | In-stock |
| 1g | $19 | In-stock |
| 5g | $55 | In-stock |
| 10g | $110 | In-stock |
| 25g | $275 | In-stock |
| 100g | $931 | In-stock |
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| 500 g | Get quote | |
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| Cat. No. : | HY-W018174 |
| M.Wt: | 163.21 |
| Formula: | C7H17NO3 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
m-PEG3-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG3-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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