Dimethothiazine
CAS No. : 7456-24-8
(Synonyms: Dimetotiazine; Fonazine)
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| Cat. No. : | HY-A0157 |
| M.Wt: | 391.55 |
| Formula: | C19H25N3O2S2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Dimethothiazine (Dimetotiazine; Fonazine) is an orally active tricyclic anti-histamine, anti-5-HT agent with a high activity against decerebrate rigidity, a little sedative activity and little soporific action. Dimethothiazine can reduce or abolish the effects of both static and dynamic fusimotor activity on the muscle spindle in decerebrate cat. Dimethothiazine can be used to research hemicrania and spasticity[1][2][3]. IC50 & Target:Histamine, 5-HT[1] In Vivo:Dimethothiazine (0.5-16 mg/kg; i.v.; single dosage) reduces decerebrate rigidity in cats[2].
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