Trimegestone
CAS No. : 74513-62-5
(Synonyms: RU 27987)
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| Cat. No. : | HY-106827 |
| M.Wt: | 342.47 |
| Formula: | C22H30O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Trimegestone (RU 27987) is an orally active 19-norpregnane progestin. Trimegestone binds to progesterone receptor (PR) with an IC50 value of 3.3 nM (rat PR). Trimegestone increases alkaline phosphatase activity (EC50=0.1 nM) but not luciferase activity. Trimegestone also shows a weak antiandrogenic activity (weak androgen receptor affinity). Trimegestone can be used in studies of contraception or menopausal syndromes[1][2].
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