UBP296
CAS No. : 745055-86-1
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| Cat. No. : | HY-107605 |
| M.Wt: | 333.30 |
| Formula: | C15H15N3O6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
UBP296 is a potent and selective antagonist of GLUK5-containing kainate receptor in the spinal cord. UBP296 reversibly blocks ATPA-induced depressions of synaptic transmission, and affects AMPA receptor-mediated synaptic transmission directly in rat hippocampal slices[1]. IC50 & Target: IC50: 3.5 ± 1.5 μM (GLUK5), 4.0 ± 0.7 μM (GLUK5/GLUK6), 7.0 ± 5.1 μM (GLUK5/GLUK2)[1]
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