3-Bromo-7-nitroindazole
CAS No. : 74209-34-0
| Size | Price | Stock |
|---|---|---|
| 5g | $19 | In-stock |
| 10g | $38 | In-stock |
| 25g | $65 | In-stock |
| 100g | $256 | In-stock |
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| Cat. No. : | HY-101175 |
| M.Wt: | 242.03 |
| Formula: | C7H4BrN3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
3-Bromo-7-nitroindazole is a potent and selective inhibitor of neuronal nitric oxide synthase (nNOS). 3-Bromo-7-nitroindazole affects the intercellular messenger nitric oxide (NO) synthesis throughout the body and brain. 3-Bromo-7-nitroindazole can be used for the researches of metabolic and neurological disease, such as diabetes, stroke and depression[1][2][3].
IC50 & Target:nNOS[1]
In Vivo:3-Bromo-7-nitroindazole (5-20 mg/kg, i.p., daily for 5 days) impairs spatial learning and memory in rats[1].
3-Bromo-7-nitroindazole (3-30 mg/kg, i.p.) attenuates brain ischemic injury in diabetic stroke rats[2].
3-Bromo-7-nitroindazole (20 mg/kg, i.p., daily for 5 weeks) inhibits chronic unpredictable mild stress (CUMS)-induced depression-like behavior in rats[3].
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