β-Hydroxyisovalerylshikonin


CAS No. : 7415-78-3

7415-78-3
Price and Availability of CAS No. : 7415-78-3
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1mg $171 In-stock
5mg $514 In-stock
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Cat. No. : HY-N4201
M.Wt: 388.41
Formula: C21H24O7
Purity: >98 %
Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 7415-78-3 :

Beta-hydroxyisovalerylshikonin is a natural product isolated from Lithospermum erythrorhizon, acts as a potent inhibitor of protein tyrosine kinases (PTK), with IC50s of 0.7μM and 1μM for EGFR and v-Src receptor, respectively. Beta-hydroxyisovalerylshikonin is effective against a wide variety of tumor cell lines, and most efficiently induces cell-death in NCI-H522 and DMS114 cells[1]. IC50 & Target:IC50: 0.7 μM (EGFR), 1 μM (v-Src)[1]

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