Hydrocortisone aceponate


CAS No. : 74050-20-7

(Synonyms: Hydrocortisone 17-propionate 21-acetate)

74050-20-7
Price and Availability of CAS No. : 74050-20-7
Size Price Stock
50mg $107 In-stock
100mg $144 In-stock
250mg $241 In-stock
1g $483 In-stock
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Cat. No. : HY-116691
M.Wt: 460.56
Formula: C26H36O7
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 74050-20-7 :

Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is a diester-based topical glucocorticoid. Hydrocortisone aceponate alleviates symptoms such as erythema, dryness/desquamation, pruritus, epidermal exfoliation, and exudation/crusting. Hydrocortisone aceponate causes extremely few adverse reactions. Hydrocortisone aceponate is applicable to various dermatological disease studies[1][2]. In Vitro:Hydrocortisone aceponate exerts weaker inhibitory effects on proliferation, collagen synthesis, and total protein synthesis of human skin fibroblasts than an equivalent dose of Betamethasone valerate (HY-B0727)[1]. In Vivo:Hydrocortisone aceponate (0.0584% spray; 260 µL/100 cm2; topical administration; once daily for 56 consecutive days) causes no significant skin thinning, histopathological abnormalities or local adverse reactions in healthy female Beagle dogs[1].

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