NSC45586


CAS No. : 739301-85-0

739301-85-0
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Cat. No. : HY-19820
M.Wt: 390.40
Formula: C20H18N6O3
Purity: >98 %
Solubility: DMSO : 20.83 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 739301-85-0 :

NSC45586 is an inhibitor of pleckstrin homology domain and leucine-rich repeat protein phosphatase (PHLPP). NSC45586 targets the PP2C phosphatase domain in PHLPP1 and PHLPP2. NSC45586 can activate AKT in neurons[1]. IC50 & Target:PHLPP1/2, Akt[1]

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