MS15203


CAS No. : 73912-52-4

(Synonyms: MS0015203)

73912-52-4
Price and Availability of CAS No. : 73912-52-4
Size Price Stock
5mg $75 In-stock
10mg $130 In-stock
25mg $270 In-stock
50mg $405 In-stock
100mg $600 In-stock
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Cat. No. : HY-116797
M.Wt: 249.22
Formula: C12H11NO5
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 73912-52-4 :

MS15203 is a potent and selective GPR171 agonist. MS15203 increases food intake and body weight. MS15203 increases neuronal activity. MS15203 significantly increases the abundance of the mRNAs encoding proSAAS, NPY, AgRP[1]. In Vitro: MS15203 (MS0015203) dose-dependently increases [[35]S]GTPγS binding and inhibits adenylyl cyclase activity in rat hypothalamic membranes[1]. In Vivo: MS15203 (MS0015203) (3 mg/kg; i.p.) causes an increase in neuronal activity within cells containing GPR171 in the PVN[1].
. MS15203 (3 mg/kg; i.p.) significantly increases food intake at 4 and 8 hours[1].
MS15203 (3 mg/kg; i.p.) significantly increases the abundance of the mRNAs encoding proSAAS, NPY, AgRP[1].

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