Broussonin A


CAS No. : 73731-87-0

73731-87-0
Price and Availability of CAS No. : 73731-87-0
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Cat. No. : HY-N2960
M.Wt: 258.31
Formula: C16H18O3
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 73731-87-0 :

Broussonin A is a potent BChE inhibitor, with an IC50 of 4.16 µM. Broussonin A is a diarylpropane natural product that can be isolated from the bark of Broussonetia papyrifera after solid fermentation[1][2][3]. In Vitro:Broussonin A (0.1-10 µM, 30 min) suppresses VEGF-A-stimulated endothelial cell proliferation by regulating the expression of cell cycle-related proteins and the phosphorylation status of retinoblastoma protein[1].
Broussonin A (0-10 µM, 30 min)abrogates VEGF-A-stimulated angiogenic responses including endothelial cell migration, invasion, tube formation and microvessel formation from rat aortic rings[1].

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