Indecainide (hydrochloride)


CAS No. : 73681-12-6

(Synonyms: Ricainide (hydrochloride); LY 135837)

73681-12-6
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Cat. No. : HY-16259
M.Wt: 344.88
Formula: C20H25ClN2O
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 73681-12-6 :

Indecainide hydrochloride is a potent and orally active class I local anesthetic antiarrhythmic agent. Indecainide hydrochloride has Na+-channel-blocking activity[1][2][3]. In Vivo: Indecainide hydrochloride (0, 3, 6, or 9 mg/kg; IV, daily for 1 month) causes 6 of 10 male rats and 1 of 10 female rats die at 9 mg/kg during the test period[2].
Indecainide hydrochloride (0, 1.5, 3, or 4.5 mg/kg; IV, daily for 1 month) causes 2 of 4 dogs die at 4.5 mg/kg; exhibits no overt signs of toxicity and no hematologic, serum chemistry or histologic changes at 1.5 or 3 mg/kg[2].

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