HEPES


CAS No. : 7365-45-9

7365-45-9
Price and Availability of CAS No. : 7365-45-9
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Cat. No. : HY-D0857
M.Wt: 238.30
Formula: C8H18N2O4S
Purity: >98 %
Solubility: H2O : 250 mg/mL (ultrasonic)
Introduction of 7365-45-9 :

HEPES, a nonvolatile zwitterionic chemical buffering agent, is broadly applied in cell culture. HEPES is effective at pH 6.8 to 8.2. HEPES is also a potent inducer of lysosome biogenesis[1][2][3]. In Vitro: HEPES maintains superhydrophilicity of titanium for at least 3 months and resulted in a continuous retention of bioactivity and osteoconductivity[1].
HEPES drives lysosome biogenesis, affects MiT/TFE cytoplasmic-nuclear distribution, disrupts global cellular transcriptional profiles, resulting the activation of a MiT/TFE-dependent lysosomal-autophagic gene network in cultured RAW264.7 cells[3].

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