Methylnissolin
CAS No. : 73340-41-7
(Synonyms: Astrapterocarpan)
| Size | Price | Stock |
|---|---|---|
| 1mg | $100 | In-stock |
| 5mg | $260 | In-stock |
| 10mg | $400 | In-stock |
| 25mg | $663 | In-stock |
| 50mg | $945 | In-stock |
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| Cat. No. : | HY-N2484 |
| M.Wt: | 300.31 |
| Formula: | C17H16O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Methylnissolin (Astrapterocarpan), isolated from Astragalus membranaceus, inhibits platelet-derived growth factor (PDGF)-BB-induced cell proliferation with an IC50 of 10 μM. Methylnissolin inhibits PDGF-BB-induced phosphorylation of extracellular signal-regulated kinase 1/2 (ERIC1/2) mitogen-activated protein (MAP) kinase. Methylnissolin inhibits PDGF-BB-induced vascular smooth muscle cell proliferation by inhibition of the ERK1/2 MAP kinase cascade[1].
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