EGFR-IN-198
CAS No. : 733009-42-2
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| Cat. No. : | HY-112334 |
| M.Wt: | 399.63 |
| Formula: | C16H10Cl3FN4O |
| Purity: | >98 % |
| Solubility: |
EGFR-IN-198 is a selective EGFR inhibitor with subnanomolar irreversible inhibitory activity against EGFR. EGFR-IN-198 covalently binds to the kinase domain of EGFR and inhibits its autophosphorylation[1]. In Vitro:EGFR-IN-198 (compound 4a) potently inhibits EGFR autophosphorylation in A431 cell lysates with an IC50 of 0.07 nM[1].
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- EGFR-IN-198
- Cat. No.:
- HY-112334
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