Have any questions? [email protected] +86-21-58998590
Structure search

Atractylenolide III


CAS No. : 73030-71-4

(Synonyms: ICodonolactone; 8β-Hydroxyasterolide)

73030-71-4
Price and Availability of CAS No. : 73030-71-4
Size Price Stock
5mg $64 In-stock
10mg $97 In-stock
25mg $158 In-stock
50mg $232 In-stock
100mg $343 In-stock
200 mg Get quote
500 mg Get quote
We match the lowest price on market.

We offer a substantial discount on larger orders, please inquire via [email protected]

or Fax: (86)21-58955996

Inquiry for price and availability only. Please place your order via our email or fax.

Cat. No. : HY-N0203
M.Wt: 248.32
Formula: C15H20O3
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic)
Introduction of 73030-71-4 :

Atractylenolide III (ICodonolactone) is the main component of Atractylodes rhizome and has the activity of inducing apoptosis in lung cancer cells. Atractylenolide III is an orally active gastroprotective agent[1][2][3]. In Vitro:Atractylenolide III (1-100 μM, 48 h ) induces cell apoptosis, and induces the activation of caspase-3 and caspase-9 and cleavage of PARP in A549 cells[1].
Atractylenolide III (1-100 μM, 72 h) inhibits proliferation and angiogenesis (tube formation) in HUVECs[1].
Atractylenolide III (1-100 μM) inhibits thymic stromal lymphopoietin (TSLP)-induced production of proinflammatory cytokines (IL-6, IL-1b, TNF-α, and IL-8) in HMC-1 cells[4].
In Vivo:Atractylenolide III (5 and 10 mg/kg, p.o.) shows gastroprotective effects and reduces 70% ethanol-induced gastric ulcer in rats[2].
Atractylenolide III (30 mg/kg, oral gavage for 14 days or 28 days) reduces depressive- and anxiogenic-like behaviors in rat depression models in Lipopolysaccharide (LPS) (HY-D1056) and chronic unpredictable mild stress (CUMS) induced rat depression model[5].

Your information is safe with us.