Bendroflumethiazide


CAS No. : 73-48-3

(Synonyms: Bendrofluazide)

73-48-3
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Cat. No. : HY-B1363
M.Wt: 421.41
Formula: C15H14F3N3O4S2
Purity: >98 %
Solubility: DMSO : 250 mg/mL (ultrasonic)
Introduction of 73-48-3 :

Bendroflumethiazide (Bendrofluazide) is an orally available diuretic. Bendroflumethiazide inhibits the electroneutral sodium-chloride symporter located in the apical membrane of the early segment of the distal convoluted tubule and can effectively lower blood pressure. Bendroflumethiazide is used in the study of hypertension and edema. Bendroflumethiazide has an antidiuretic effect in diabetes insipidus[1][2]. In Vivo:Bendroflumethiazide (125 mg/kg, p.o. 12 days) reduces body weight, decreases urine flow, and increases urine osmolality in the Brattleboro rat model of diabetes insipidus, exerts an antidiuretic effect through sustained sodium loss[2].

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