Porcine dynorphin A(1-13)
CAS No. : 72957-38-1
(Synonyms: Dynorphin A Porcine Fragment 1-13)
| Size | Price | Stock |
|---|---|---|
| 1mg | $84 | In-stock |
| 5mg | $180 | In-stock |
| 10mg | $288 | In-stock |
| 25mg | $588 | In-stock |
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| Cat. No. : | HY-P0088 |
| M.Wt: | 1603.95 |
| Formula: | C75H126N24O15 |
| Purity: | >98 % |
| Solubility: | H2O : ≥ 60 mg/mL |
Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. IC50 & Target:Κ opioid receptor[1]. In Vivo: Dynorphin A (1-13) exposure (33 μM) causes a significant loss in neuronal viability at 4 h with a visible destruction in neuronal morphology seen at 16 h. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment. Continuous exposure to dynorphin A (1-13) (100 μM) causes a significant loss of neurons over time[1].
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