(±)-Catechin
CAS No. : 7295-85-4
(Synonyms: rel-Cianidanol; rel-Catechuic acid)
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| Cat. No. : | HY-B1890 |
| M.Wt: | 290.27 |
| Formula: | C15H14O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
(±)-Catechin (rel-Cianidanol) is the racemate of the green tea polyphenol Catechin. Catechin has anticancer activity and induces apoptosis. (±)-Catechin has two forms, (+)-Catechin and its enantiomer (-)-Catechin. (+)-Catechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM. (-)-Catechin can effectively promote hBM-MSC adipocyte differentiation and increase adiponectin and PPARγ levels. (±)-Catechin has anti-tumor, anti-obesity, anti-diabetic, anti-cardiovascular, anti-infectious, hepatoprotective and neuroprotective effects[1][2][3].
In Vitro:(-)-catechin (10 μM; a 2-day cycle for 12 days in total) induces adipocyte differentiation of human bone marrow mesenchymal stem cells (hBM-MSC), increases adiponectin levels, and increased PPARγ transcription[2].
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