MLS0315771
CAS No. : 727664-91-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $140 | In-stock |
| 10mg | $210 | In-stock |
| 25mg | $390 | In-stock |
| 50mg | $520 | In-stock |
| 100mg | $690 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-112945 |
| M.Wt: | 273.33 |
| Formula: | C15H12FNOS |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
MLS0315771 is a potent and biologically active competitive phosphomannose isomerase (MPI) inhibitor, with an IC50 ~1 μM and a Ki of 1.4 μM.
IC50 & Target: IC50: ~1 μM (MPI)[1].
In Vitro: MLS0315771 increases mannose flux toward glycosylation.
MLS0315771 toxicity at higher concentrations is an off-target effect.
MLS0315771 is toxic to the zebrafish embryos above 2 μM. At 8-10 μM, ~50% embryos appeare sick within 20 min, and most of them die by 30-60 min[1].
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