Thr101


CAS No. : 727664-79-1

727664-79-1
Price and Availability of CAS No. : 727664-79-1
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5mg $140 In-stock
10mg $225 In-stock
25mg $450 In-stock
50mg $720 In-stock
100mg $1152 In-stock
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Cat. No. : HY-124890
M.Wt: 259.30
Formula: C14H10FNOS
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 80°C)
Introduction of 727664-79-1 :

Thr101 is an inhibitor (IC50=2.9 μM) of phosphomannose isomerase (PMI).PMI can compete with phosphomannose mutase 2 (PMM2) for the binding site of Man-6-P and convert mannose-6-phosphate (Man-6-P) into fructose-6-phosphate (Fru-6-P) .Thr101 only specifically inhibits PMI and not PMM2. Thr101 can be used for research of congenital disorder of glycosylation type Ia (CDG-Ia)[1]. IC50 & Target:ic50: 2.9 μM (Phosphomannose isomerase, PMI)[1]

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