| Size | Price | Stock |
|---|---|---|
| 25mg | $25 | In-stock |
| 50mg | $35 | In-stock |
| 100mg | $50 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-W013766 |
| M.Wt: | 357.36 |
| Formula: | C14H23N5O6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Pipemidic acid trihydrate, a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid trihydrate inhibits DNA gyrase. Pipemidic acid trihydrate is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid trihydrate can be used for the research of intestinal, urinary, and biliary tract infections[1][2].
In Vitro:Pipemidic acid trihydrate is an inhibitor of DNA gyrase that is a bacterial enzyme which catalyzes the ATP-dependent negative supercoiling of DNA[2].
In Vivo:Pipemidic acid (50 mg/kg) trihydrate is absorbed well by the oral route, and the peak levels in plasma ranged from 4 to 12 μg/mL in mice, rats, dogs, monkeys[3].
The mean lethal dose of Pipemidic acid trihydrate after a single oral dose was more than 16000 mg/kg in mice[3].
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