Rifabutin
CAS No. : 72559-06-9
(Synonyms: Ansamycin; LM-427)
| Size | Price | Stock |
|---|---|---|
| 10mg | $35 | In-stock |
| 25mg | $60 | In-stock |
| 50mg | $84 | In-stock |
| 100mg | $120 | In-stock |
| 500mg | $312 | In-stock |
| 1 g | Get quote | |
| 5 g | Get quote | |
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| Cat. No. : | HY-17025 |
| M.Wt: | 847.00 |
| Formula: | C46H62N4O11 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase. IC50 & Target:Antibacterial In Vitro: Rifabutin is primarily bactericidal antibiotic drug used to treat tuberculosis. Its effect on bacteria is based on the DNA-dependent RNA polymerase blocking drug rifamycin S., a semi-synthetic derivative. It is effective, for example, in highly resistant mycobacteria, Gram-positive bacteria (and some are effective against Gram-negative bacteria), but also against Mycobacterium tuberculosis, M. leprae, and M. avium intracellulare. Rifabutin is an antibiotic; antitumor. Rifabutin interferes with HSP-90 molecular chaperone, enhances ubiquitination and protein degradation, and inactivates bacterial RNA polymerase.
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