BAY-8002


CAS No. : 724440-27-1

724440-27-1
Price and Availability of CAS No. : 724440-27-1
Size Price Stock
5mg $95 In-stock
10mg $140 In-stock
50mg $430 In-stock
100mg $700 In-stock
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Cat. No. : HY-122312
M.Wt: 415.85
Formula: C20H14ClNO5S
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 724440-27-1 :

BAY-8002 is a potent, selective, orally active inhibitor of monocarboxylate transporter 1 (MCT1), with an IC50 of 85 nM in the MCT1-expressing DLD-1 cells, displays excellent selectivity against MCT4. Anti-tumor activity[1]. IC50 & Target: IC50: 85 nM (MCT1, in DLD-1 cells)[1] In Vitro: BAY-8002 is an inhibitor of MCT1, with an IC50 of 85 nM in the MCT1-expressing DLD-1 cells, displays excellent selectivity against MCT4 (IC50 >50 µM in EVSA-T cells)[1]. In Vivo: BAY-8002 (80 and 160 mg/kg, p.o., twice daily, for more than 26 days) significantly inhibits tumor growth in Raji tumor-bearing mice[1].

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