Anthracene-9-carboxylic acid
CAS No. : 723-62-6
(Synonyms: 9-Anthracenecarboxylic acid)
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| 25g | $25 | In-stock |
| 100g | $75 | In-stock |
| 500g | $295 | In-stock |
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| Cat. No. : | HY-101329 |
| M.Wt: | 222.24 |
| Formula: | C15H10O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
Anthracene-9-carboxylic acid (9-Anthracenecarboxylic acid) is an anthracene derivative traditionally used to block and identify Ca2+-activated Cl- currents (CaCCs) in various cell types, like diverse smooth muscle cells, epithelial cells and salivary gland cells[1].
IC50 & Target:Ca2+-activated Cl- currents[1]
In Vitro:Anthracene-9-carboxylic acid causes a voltage-dependent block of outward currents in HEK 293T cells and inhibits a larger fraction of the current as depolarization increased[1].
Anthracene-9-carboxylic acid induces a strong potentiation of tail currents measured at -100 mV after depolarizing voltages, as well as a prolongation of the deactivation kinetics in HEK 293T[1].
Anthracene-9-carboxylic acid (500 μM, rabbit pulmonary artery smooth muscle cells) produces a small inhibition of the maximum outward Cl- current at +70 mV (21±10%) but augmented the amplitude of the instantaneous inward relaxation at -80 mV by 321±34%[2].
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