Ferumoxytol


CAS No. : 722492-56-0

722492-56-0
Price and Availability of CAS No. : 722492-56-0
Size Price Stock
1mg $60 In-stock
5mg $133 In-stock
10mg $212 In-stock
25mg $425 In-stock
50mg $680 In-stock
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Cat. No. : HY-108894
M.Wt: 1000.00
Formula: N/A
Purity: >98 %
Solubility:
Introduction of 722492-56-0 :

Ferumoxytol is an iron oxide nanoparticle. Ferumoxytol has anti-leukemic activity, especially against acute myeloid leukemia (AML) cells with low iron transporter protein (FPN) expression. Ferumoxytol increases intracellular iron content, triggers the Fenton reaction, generates reactive oxygen species (ROS), leads to oxidative stress and ferroptosis. Ferumoxytol can selectively kill leukemic cells with low FPN expression while avoiding toxicity to normal cells. Ferumoxytol can be used to study leukemias with targeted iron metabolism abnormalities[1].

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