Vadocaine
CAS No. : 72005-58-4
(Synonyms: OR K-242)
| Size | Price | Stock |
|---|---|---|
| 1mg | $274 | Get quote |
| 5mg | $693 | Get quote |
| 10mg | $1020 | Get quote |
| 25mg | $1645 | Get quote |
| 50mg | $2274 | Get quote |
| 100 mg | Get quote | |
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| Cat. No. : | HY-106495 |
| M.Wt: | 304.43 |
| Formula: | C18H28N2O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Vadocaine (OR K-242), an orally active antitussive compound, is a local agent that can suppress or relieve pain[1].
In Vivo:In guinea-pigs, Vadocaine (2.5 mg/kg; p.o.) reduces by about 70% the cough episodes induced by sulphur dioxide or ammonia[1].
In cats, Vadocaine (3 mg/kg; i.v.) inhibits by about 80% for 10 min the cough reflex initiated by mechanical irritation of the trachea[1].
Vadocaine causes local anaesthesia in the guinea-pig wheal preparation at concentrations of 0.25% and 0.5%, and on the guinea-pig cornea at 0.5%[1].
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