2'-Deoxyadenosine 5'-di-phos-phate (disodium)
CAS No. : 72003-83-9
(Synonyms: dADP (disodium))
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| Cat. No. : | HY-W010854 |
| M.Wt: | 455.17 |
| Formula: | C10H13N5Na2O9P2 |
| Purity: | >98 % |
| Solubility: | H2O : 250 mg/mL (ultrasonic) |
2'-Deoxyadenosine 5'-diphosphate disodium (dADP disodium) is an inhibitor of Polynucleotide phosphorylase and Polyadenylate polymerase. 2'-Deoxyadenosine 5'-diphosphate disodium inhibits polyadenylate synthesis in permeabilized bacterial cells. As a chelating agent, 2'-Deoxyadenosine 5'-diphosphate disodium forms 1:1 complexes with trivalent lanthanides, Manganese (II) and Copper (II) ions, with unique coordination modes and structural conformations for each ion type[1][2]. In Vitro:2'-Deoxyadenosine 5'-diphosphate (0.25 mM) disodium strongly inhibits poly(A) synthesis in toluene-treated permeable Escherichia coli cells, with 0.25 mM dADP reducing activity by over 90%[1].
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