Mefruside
CAS No. : 7195-27-9
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| Cat. No. : | HY-123179 |
| M.Wt: | 382.88 |
| Formula: | C13H19ClN2O5S2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Mefruside is an orally active diuretic and has a mild hypotensive effect. Mefruside inhibits the synthesis of urea in an isolated rat liver perfusion model. Mefruside can be used in studies of oedema and hypertension[1][2].
In Vitro: Mefruside (0.3 mM; 50 min) shows 34% inhibition of urea synthesis in isolated perfused rat liver[1].
Mefruside (0.25, 0.5, 0.75, 1, 1.25 mM) inhibits urea synthesis in a concentration-dependent manner in isolated perfused rat liver[1].
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