Moclobemide
CAS No. : 71320-77-9
(Synonyms: Ro111163)
| Size | Price | Stock |
|---|---|---|
| 5mg | $32 | In-stock |
| 10mg | $50 | In-stock |
| 25mg | $90 | In-stock |
| 50mg | $140 | In-stock |
| 100mg | $210 | In-stock |
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| Cat. No. : | HY-B0534 |
| M.Wt: | 268.74 |
| Formula: | C13H17ClN2O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Moclobemide (Ro111163) is a brain-penetrant and reversible monoamine oxidase (MAO-A) inhibitor with an IC50 of 6.061 μM for hMAO-A[1].Moclobemide up-regulates proliferation of hippocampal progenitor cells in chronically stressed mice. In Vitro: NMDA (600 µM for 3 days) inhibits the proliferation of PC12 cells.Moclobemide (2 and 10 µM) up-regulates the proliferation in NMDA-treated PC12 cells[2]. In Vivo: Moclobemide is a monoamine oxidase inhibitor and increases the levels of brain monoamines (such as 5-HT, norepinephrine).Moclobemide(40 mg/kg) is effective in animal behavior models[2].
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